Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.44 |
| ▸ | PDE2A | O00408 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174355 | 0.84 | HTR2C (0.42) | HTR2CPDE2ATP53BCDIN3DGAA | |
| SCHEMBL173618 | 0.83 | SIGMAR1 (0.31) | PDE2A | |
| SCHEMBL23579577 | 0.80 | PDE2A (0.47) | HTR2CPDE2ABCDIN3DGAA | |
| SCHEMBL30033642 | 0.80 | PDE2A (0.47) | HTR2CPDE2ABCDIN3DGAA | |
| SCHEMBL174842 | 0.77 | GAA (0.43) | GAA | |
| SCHEMBL164859 | 0.74 | ADORA3 (0.43) | — | |
| SCHEMBL173716 | 0.73 | PLK4 (0.58) | HTR2C | |
| SCHEMBL174952 | 0.71 | PIK3CA (0.42) | — | |
| SCHEMBL164199 | 0.71 | CCNE2 (0.41) | GAA | |
| SCHEMBL164991 | 0.69 | GRM2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303533-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303533-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | JAK3, JAK2, JAK1 | HTR2C 2439/4885PDE2A 1743/4885TP53 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.