Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747319 | 0.78 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1747320 | 0.67 | PDE4B (1.00) | PDE4B | |
| SCHEMBL1747312 | 0.64 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29965443 | 0.60 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21212158 | 0.60 | TLR8 (0.43) | TLR8NR1H2NR1H3 | |
| SCHEMBL8820190 | 0.60 | TLR8 (0.54) | TLR8 | |
| SCHEMBL22048859 | 0.59 | HTR1A (0.36) | PDE4B | |
| SCHEMBL30150121 | 0.59 | TLR8 (0.52) | TLR8 | |
| SCHEMBL28930700 | 0.59 | TLR8 (0.52) | TLR8 | |
| SCHEMBL28677927 | 0.59 | PDE4B (0.49) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |