Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | HEXA | P06865 | 1/20 | 0.34 |
| ▸ | HEXB | P07686 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747540 | 0.79 | L3MBTL1 (0.47) | L3MBTL1 | |
| SCHEMBL13157188 | 0.79 | L3MBTL1 (0.47) | L3MBTL1 | |
| SCHEMBL7687547 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL735726 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL7085221 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL24205780 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL6037671 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL730123 | 0.79 | MAPK1 (0.47) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL21295215 | 0.76 | MAPK1 (0.45) | MAPK1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL2464372 | 0.76 | MAPK1 (0.45) | MAPK1LGALS1LGALS3LGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2384743-A1 | Siosomal formulation for intracellular delivery and targeting of therapeutic agents | Salama, Zoser B. (DE) | 2011-11-09 | — | — | EP | disclosed |