SCHEMBL1747540

SCHEMBL1747540

CC(C)[Si](C)(C)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ MAPT P10636 1/20 0.46
▸ TYR P14679 3/20 0.43
▸ GAA P10253 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13157188 1.00 L3MBTL1 (0.47) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL22659959 0.86 L3MBTL1 (0.47) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL4959971 0.82 L3MBTL1 (0.53) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL28177022 0.82 L3MBTL1 (0.53) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL22710167 0.82 L3MBTL1 (0.53) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL7149877 0.82 L3MBTL1 (0.53) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL5514021 0.82 L3MBTL1 (0.53) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL4296816 0.80 L3MBTL1 (0.45) L3MBTL1MAPTTYRGAAPOLB
SCHEMBL1747537 0.79 MAPK1 (0.42) L3MBTL1
SCHEMBL23481289 0.77 L3MBTL1 (0.51) L3MBTL1MAPTTYRGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 — — EP disclosed
EP-2384743-A1 Siosomal formulation for intracellular delivery and targeting of therapeutic agents Salama, Zoser B. (DE) 2011-11-09 — — EP disclosed
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