Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ACACB | O00763 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166144 | 0.91 | L3MBTL1 (0.70) | L3MBTL1MAPTALDH1A1PARP10GAA | |
| SCHEMBL9149730 | 0.85 | L3MBTL1 (0.63) | L3MBTL1MAPTALDH1A1PARP10GAA | |
| SCHEMBL24243599 | 0.85 | MAPT (0.73) | L3MBTL1MAPTALDH1A1PARP10GAA | |
| SCHEMBL31160399 | 0.82 | NQO1 (0.74) | ACACB | |
| SCHEMBL7740048 | 0.82 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1GAAACACB | |
| SCHEMBL12769347 | 0.82 | GAA (0.73) | L3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7733794 | 0.82 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1GAAACACB | |
| 1,4-Diethoxybenzene SCHEMBL28832463 | 0.81 | MAOB (0.64) | L3MBTL1MAPTALDH1A1PARP10GAA | |
| SCHEMBL10994870 | 0.81 | LMNA (0.62) | L3MBTL1MAPTALDH1A1PARP10GAA | |
| SCHEMBL4105152 | 0.78 | MAPT (0.77) | MAPTALDH1A1GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611771-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012028676-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |