SCHEMBL17477102

SCHEMBL17477102

Cc1ccccc1-c1ccn(-c2cccnc2)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.43
CYP3A4 P08684 4/20 0.43
HTT P42858 2/20 0.43
CYP2E1 P05181 2/20 0.43
CYP1A2 P05177 3/20 0.39
CYP17A1 P05093 1/20 0.39
CYP2C19 P33261 2/20 0.39
CLK4 Q9HAZ1 1/20 0.39
CYP11B2 P19099 2/20 0.39
KDM4E B2RXH2 2/20 0.39
NPY5R Q15761 1/20 0.39
CYP11B1 P15538 1/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
AHR P35869 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
IDO1 P14902 2/20 0.38
TDO2 P48775 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31707269 0.76 CYP2A6 (0.51) CYP2A6CYP3A4HTTCYP2E1KDM4E
SCHEMBL2689916 0.76 CYP2A6 (0.51) CYP2A6CYP3A4HTTCYP2E1KDM4E
SCHEMBL17477103 0.74 NPC1 (0.47) CYP2A6CYP3A4CYP2E1KDM4ENPY5R
SCHEMBL6677484 0.72 ALDH1A1 (0.50) CYP2A6CYP3A4HTTCYP1A2KDM4E
SCHEMBL23234420 0.70 HTT (0.38) CYP2A6CYP3A4HTTCYP2E1CYP1A2
SCHEMBL30754177 0.70 HTT (0.38) CYP2A6CYP3A4HTTCYP2E1CYP1A2
SCHEMBL17268488 0.70 CYP2A6 (0.46) CYP2A6CYP3A4HTTCYP2E1MAPT
SCHEMBL12854024 0.70 HTT (0.50) HTTKDM4EHPGDTSHRMAPT
SCHEMBL16574032 0.70 KMT2A (0.55) CYP3A4HTTCYP1A2CYP2C19CLK4
SCHEMBL29767299 0.70 KMT2A (0.55) CYP3A4HTTCYP1A2CYP2C19CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3186229-A4 PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE Dow AgroSciences LLC (US) 2018-01-10 EP disclosed
EP-3186229-A1 PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE Dow AgroSciences LLC (US) 2017-07-05 EP disclosed
WO-2016018443-A1 PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE DOW AGROSCIENCES LLC (US) 2016-02-04 WO disclosed