Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959449 | 0.80 | GRM5 (0.60) | ALDH1A1CYP3A4IDO1 | |
| SCHEMBL182558 | 0.80 | KMO (0.59) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30677227 | 0.77 | XDH (0.36) | NPC1RAB9AALDH1A1L3MBTL1NFKB1 | |
| SCHEMBL6677484 | 0.76 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1CYP2A6 | |
| SCHEMBL27832175 | 0.75 | FYN (0.53) | NPC1RAB9ACYP2A6MAPTCYP3A4 | |
| SCHEMBL5199932 | 0.75 | MEN1 (0.54) | NPC1RAB9AALDH1A1L3MBTL1NFKB1 | |
| SCHEMBL17477102 | 0.74 | CYP2A6 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2CYP2A6 | |
| SCHEMBL2689916 | 0.74 | CYP2A6 (0.51) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL31707269 | 0.74 | CYP2A6 (0.51) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL182019 | 0.73 | MEN1 (0.59) | NPC1RAB9AALDH1A1L3MBTL1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186229-A4 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-3186229-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016018443-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |