Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 6/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484410 | 0.92 | ELANE (0.42) | ELANEKMT2AATMMMP12MMP13 | |
| SCHEMBL17484452 | 0.86 | MAOB (0.37) | KMT2AMMP12MMP13THRBACACB | |
| SCHEMBL26362231 | 0.85 | ELANE (0.53) | ELANEKMT2AATMTHRBACACB | |
| SCHEMBL26362357 | 0.85 | ELANE (0.53) | ELANEKMT2AATMTHRBACACB | |
| SCHEMBL17484464 | 0.84 | ELANE (0.49) | ELANEKMT2AATMTHRBACACB | |
| SCHEMBL17484400 | 0.83 | RARB (0.37) | MMP12MMP13 | |
| SCHEMBL10020925 | 0.82 | PPARA (0.48) | ELANEKMT2AATMTHRBPTGS2 | |
| SCHEMBL17484413 | 0.82 | POLB (0.40) | MMP12MMP13THRBMMP2MMP9 | |
| SCHEMBL883697 | 0.81 | THRB (0.58) | ELANEKMT2AATMTHRBACACB | |
| SCHEMBL20827825 | 0.81 | THRB (0.58) | ELANEKMT2AATMTHRBACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536679-B | Liquid-crystalline medium with homeotropic alignment | 默克专利股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3174955-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |