Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 7/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484775 | 0.87 | HTT (0.62) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL17478177 | 0.87 | HTT (0.62) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL17478072 | 0.81 | LMNA (0.49) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL3895930 | 0.81 | GPBAR1 (0.67) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL3342133 | 0.77 | LMNA (0.58) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL3888823 | 0.74 | GPBAR1 (0.65) | GPBAR1LMNAHTTTP53 | |
| SCHEMBL5661329 | 0.74 | ADRA1A (0.52) | GPBAR1LMNAHTTTP53 | |
| SCHEMBL7928701 | 0.74 | ADRA1A (0.52) | GPBAR1LMNAHTTTP53 | |
| SCHEMBL17478253 | 0.72 | RPS6KB1 (0.55) | GPBAR1LMNAHTTROCK1RPS6KA1 | |
| SCHEMBL4312703 | 0.70 | RPS6KB1 (0.58) | GPBAR1LMNAHTTROCK1RPS6KA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174872-A1 | 2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE | Université de Lille 2 Droit et Santé (FR) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016238-A1 | 2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2016-02-04 | — | — | WO | disclosed |