Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175211 | 0.77 | PDE4B (0.40) | F2RL3NPC1RAB9ASTIM1ORAI1 | |
| SCHEMBL24425236 | 0.73 | NLRP3 (0.44) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL174226 | 0.72 | AR (0.38) | F2RL3PDE4BPDE4D | |
| SCHEMBL15862756 | 0.71 | KMT2A (0.43) | — | |
| SCHEMBL28972344 | 0.69 | CCR1 (0.36) | SCN9ACYP1A2 | |
| SCHEMBL24409354 | 0.69 | NR1H4 (0.42) | SMN1; SMN2 | |
| SCHEMBL15862417 | 0.66 | NPY5R (0.49) | NPC1RAB9ASTIM1ORAI1PDE4D | |
| SCHEMBL24409202 | 0.66 | NR1H4 (0.56) | SMN1; SMN2 | |
| SCHEMBL28593290 | 0.66 | COMT (0.44) | SCN9ANPC1CYP1A2RAB9APDE4B | |
| SCHEMBL24408958 | 0.65 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9131693-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2611297-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8754115-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | F2RL3 1431/4885SCN9A 1134/4885MAP4K1 2676/4885 |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | F2RL3 1431/4885SCN9A 1134/4885MAP4K1 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.