Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667031 | 0.96 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL19680523 | 0.90 | ALDH1A1 (0.53) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478705 | 0.88 | ALDH1A1 (0.63) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17479128 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478607 | 0.86 | ALDH1A1 (0.70) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478809 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478746 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL19667075 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478946 | 0.84 | RAD52 (0.61) | ALDH1A1HPGDNPSR1KDM4EHTT | |
| SCHEMBL17478971 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDNPSR1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752640-B2 | Compounds active towards bromodomains | NUEVOLUTION A/S (DK) | 2020-08-25 | — | — | US | disclosed |
| US-20170349607-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION A/S (DK) | 2017-12-07 | — | — | US | disclosed |
| EP-3174868-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | Nuevolution A/S (DK) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016316-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION A/S (DK) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349607-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | BRD4, BRD3, BRDT | ALDH1A1 3848/4885HPGD 2141/4885NPSR1 4111/4885 |
| US-10752640-B2 | Compounds active towards bromodomains | BRD4, BRD3, BRDT | ALDH1A1 3848/4885HPGD 2141/4885NPSR1 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.