Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747895 | 1.00 | CYP2D6 (0.33) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747896 | 1.00 | CYP2D6 (0.33) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747750 | 0.91 | AKR1C3 (0.37) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747747 | 0.91 | AKR1C3 (0.37) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747749 | 0.91 | AKR1C3 (0.37) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747730 | 0.85 | FFAR2 (0.34) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747731 | 0.85 | FFAR2 (0.34) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747733 | 0.85 | FFAR2 (0.34) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747860 | 0.84 | CYP3A4 (0.32) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1747859 | 0.84 | CYP3A4 (0.32) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902233-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902233-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1572656-B1 | COMPOUNDS USEFUL AS PESTICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20090318466-A1 | COMPOUNDS USEFUL AS PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090318466-A1 | COMPOUNDS USEFUL AS PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-12-24 | — | — | US | disclosed |
| US-7557132-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2009-07-07 | — | — | US | disclosed |
| US-7557132-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2009-07-07 | — | — | US | disclosed |
| US-20060063741-A1 | Compounds useful as pesticides | BENKO ZOLTAN L | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063741-A1 | Compounds useful as pesticides | DDT, ACHE, BCHE | CYP2D6 1988/4885CYP3A4 1161/4885SLC6A2 3783/4885 |
| US-20090318466-A1 | COMPOUNDS USEFUL AS PESTICIDES | DDT, ACHE, BCHE | CYP2D6 1988/4885CYP3A4 1161/4885SLC6A2 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.