Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479464 | 0.81 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL473972 | 0.80 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL23753577 | 0.80 | MEN1 (0.57) | KMT2AMEN1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL17479453 | 0.79 | MAOB (0.54) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL18758272 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPK1CYP3A4HPGD | |
| SCHEMBL7170047 | 0.79 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL31266502 | 0.79 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL29042305 | 0.78 | KMT2A (0.43) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL22406996 | 0.77 | HSP90AA1 (0.53) | KMT2AMEN1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL17242255 | 0.77 | MEN1 (0.53) | KMT2AMEN1ALDH1A1NR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180317-A1 | FACTOR XIa INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016015593-A1 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-02-04 | — | — | WO | disclosed |