SCHEMBL23753577

SCHEMBL23753577

NC(=O)Oc1ccc(Cl)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
KMO O15229 2/20 0.46
HSP90AA1 P07900 1/20 0.46
CHRNA3 P32297 1/20 0.45
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
KIF11 P52732 1/20 0.42
HTR2A P28223 2/20 0.41
SLC6A4 P31645 2/20 0.41
KCNH2 Q12809 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP3A5 P20815 1/20 0.41
CYP2C19 P33261 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688992 0.84 MEN1 (0.53) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL17242255 0.84 MEN1 (0.53) MEN1KMT2AHSP90AA1ALDH1A1LMNA
SCHEMBL28890049 0.84 MEN1 (0.53) MEN1KMT2AHSP90AA1KDM4EALDH1A1
SCHEMBL31266502 0.82 MEN1 (0.52) MEN1KMT2AALDH1A1LMNAHTR2A
SCHEMBL5260935 0.82 MEN1 (0.52) MEN1KMT2ACHRNA3PPARGPPARA
SCHEMBL7170047 0.82 MEN1 (0.52) MEN1KMT2AALDH1A1LMNAHTR2A
SCHEMBL23753572 0.82 MCL1 (0.56) MEN1KMT2AKDM4EALDH1A1MRGPRX4
SCHEMBL19810305 0.82 MEN1 (0.52) MEN1KMT2ATSHRKIF11HTR2A
SCHEMBL1587868 0.81 KDM4E (0.47) KMOHSP90AA1CHRNA3PPARGPPARA
SCHEMBL17479481 0.80 KMT2A (0.48) MEN1KMT2AKDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114007424-A Herbicide combinations UPL有限公司 2022-02-01 CN claimed
CN-107721077-A A kind of underground engineering wastewater treatment integrating device and operating method 徐州工程学院 2018-02-23 CN claimed
CN-106166428-B A kind of industrial dust purification fire prevention hybrid system and its method of work 江苏建筑职业技术学院 2017-12-26 CN claimed
CN-101632016-B Optical isomer separating filler DAICEL CHEM 2013-12-25 CN claimed
CN-101632016-A Optical isomer separating filler DAICEL CHEM 2010-01-20 CN claimed
CN-114874172-B Oridonin derivative, preparation method and medical application thereof 庞磊 2023-09-05 CN disclosed
CN-114874172-A Oridonin derivative, preparation method and medical application thereof 南充市中心医院 2022-08-09 CN disclosed
CN-114007424-A Herbicide combinations UPL有限公司 2022-02-01 CN disclosed
US-20210253528-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2021-08-19 US disclosed
CN-101632016-B Optical isomer separating filler DAICEL CHEM 2013-12-25 CN disclosed
CN-101180318-B Chitosan derivative and method for producing same UNIV NAGOYA NAT UNIV CORP 2012-05-23 CN disclosed
CN-101632016-A Optical isomer separating filler DAICEL CHEM 2010-01-20 CN disclosed
CN-101180318-A Chitosan derivative and method for producing same UNIV NAGOYA NAT UNIV CORP (JP) 2008-05-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253528-A1 CHEMICAL COMPOUNDS ATF4, EIF2AK4, ATF1 MEN1 3941/4885KMT2A 4235/4885KMO 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.