Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.52 |
| ▸ | KLK1 | P06870 | 7/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17480787 | 1.00 | F11 (0.52) | F11KLK1KLKB1 | |
| SCHEMBL17477791 | 0.95 | F11 (0.58) | F11KLK1KLKB1 | |
| SCHEMBL17477807 | 0.95 | F11 (0.58) | F11KLK1KLKB1 | |
| SCHEMBL17477793 | 0.95 | F11 (0.58) | F11KLK1KLKB1 | |
| SCHEMBL20979650 | 0.92 | F11 (0.43) | F11KLK1 | |
| SCHEMBL17481104 | 0.89 | F11 (0.42) | F11KLK1 | |
| SCHEMBL17481099 | 0.87 | F11 (0.48) | F11KLK1KLKB1 | |
| SCHEMBL20979725 | 0.86 | F11 (0.49) | F11KLK1KLKB1 | |
| SCHEMBL20979584 | 0.86 | F11 (0.49) | F11KLK1KLKB1 | |
| SCHEMBL17480788 | 0.81 | F11 (0.45) | F11KLK1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016018701-A1 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-02-04 | — | — | WO | disclosed |