Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481417 | 0.94 | SLC2A1 (0.51) | SLC2A1GAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10702781 | 0.87 | SLC2A1 (0.69) | SLC2A1GAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16019045 | 0.86 | BCHE (0.53) | SLC2A1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL20496687 | 0.86 | SLC2A1 (0.56) | SLC2A1GAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL17481406 | 0.86 | SLC2A1 (0.53) | SLC2A1GAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL3043394 | 0.81 | BCHE (0.56) | KMT2ABCHELMNAALDH1A1MEN1 | |
| SCHEMBL4908750 | 0.78 | CHRM2 (0.70) | KMT2ASMN1; SMN2MEN1CHRM2MC4R | |
| SCHEMBL10938329 | 0.76 | SLC2A1 (0.56) | SLC2A1GAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10437146 | 0.75 | KDM4E (0.71) | KMT2ASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL5114399 | 0.75 | SMN1; SMN2 (0.55) | SLC2A1KMT2ASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | ID4PHARMA LLC (US) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | SQSTM1, CTSZ, BECN1 | SLC2A1 3751/4885GAA 452/4885KMT2A 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.