Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767213 | 0.80 | NR1H3 (0.45) | KDM4EGPBAR1POLQNR1H3NR1H2 | |
| SCHEMBL17482095 | 0.80 | MLYCD (0.44) | MLYCDGPBAR1 | |
| SCHEMBL1766297 | 0.78 | GPBAR1 (0.36) | MLYCDGPBAR1HTTPOLQNPC1 | |
| SCHEMBL17482094 | 0.78 | MLYCD (0.41) | MLYCDGPBAR1RORC | |
| SCHEMBL1766434 | 0.76 | HSD17B10 (0.37) | HSD17B10KDM4EGPBAR1HTTNR1H3 | |
| SCHEMBL1766739 | 0.75 | NR1H3 (0.38) | MLYCDHSD17B10KDM4EGPBAR1HTT | |
| SCHEMBL17482100 | 0.74 | MLYCD (0.43) | MLYCDGPBAR1RORCNPC1RAB9A | |
| SCHEMBL12978268 | 0.73 | GPBAR1 (0.59) | MLYCDHSD17B10GPBAR1TRPV1POLQ | |
| SCHEMBL16155782 | 0.72 | MLYCD (0.36) | MLYCDKDM4EGPBAR1HTTRORC | |
| SCHEMBL1766674 | 0.72 | PTGS1 (0.40) | GPBAR1NR1H3NR1H2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1777/4885HSD17B10 2130/4885KDM4E 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.