Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264115 | 0.89 | HDAC6 (0.60) | KMT2ANPC1RAB9AMEN1TMPRSS2 | |
| SCHEMBL1264149 | 0.83 | HDAC6 (0.68) | KMT2ANPC1RAB9AMEN1HDAC6 | |
| SCHEMBL25605335 | 0.80 | NPC1 (0.78) | KMT2ANPC1RAB9AMEN1HDAC8 | |
| SCHEMBL29569463 | 0.80 | NPC1 (0.78) | KMT2ANPC1RAB9AMEN1HDAC8 | |
| SCHEMBL1264537 | 0.77 | HDAC6 (0.57) | KMT2ANPC1RAB9AMEN1HDAC6 | |
| SCHEMBL1264391 | 0.77 | KMT2A (0.54) | KMT2ANPC1MEN1HDAC6HDAC8 | |
| SCHEMBL12896016 | 0.77 | TAS2R8 (0.48) | TMPRSS2HDAC6HDAC8HDAC1ALDH1A1 | |
| SCHEMBL1083136 | 0.77 | HDAC6 (0.53) | KMT2ANPC1RAB9AHDAC6HDAC8 | |
| SCHEMBL20536415 | 0.77 | L3MBTL1 (0.53) | KMT2ANPC1MEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4425805 | 0.76 | KDM4E (0.60) | KMT2ANPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC5, HDAC1 | KMT2A 37/4885NPC1 1972/4885RAB9A 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.