Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748043 | 0.79 | ALDH1A1 (0.38) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL1748045 | 0.79 | ALDH1A1 (0.38) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL1748044 | 0.79 | ALDH1A1 (0.38) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL11795589 | 0.70 | ALDH1A1 (0.33) | ALDH1A1POLBHSD11B1LMNASMN1; SMN2 | |
| SCHEMBL6031208 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KMT2AMGLLHSD11B1CCR5 | |
| SCHEMBL1748242 | 0.68 | OPRD1 (0.37) | ALDH1A1POLBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL13446472 | 0.66 | CYP1A2 (0.34) | ALDH1A1 | |
| SCHEMBL2502212 | 0.65 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL4926921 | 0.64 | HDAC3 (0.39) | ALDH1A1POLBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4770419 | 0.64 | SRD5A2 (0.59) | POLBHDAC3HDAC1HDAC2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013166-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2011-09-06 | — | — | US | disclosed |
| EP-1633722-B1 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2011-08-03 | — | — | EP | disclosed |