Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 5/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483952 | 0.97 | TERT (0.34) | KDM4EMEN1RECQLKMT2APIN1 | |
| SCHEMBL17483878 | 0.93 | PPARG (0.35) | TERTPPARGPPARACDC25ACDC25B | |
| SCHEMBL17483956 | 0.93 | CDC25A (0.36) | KDM4EMEN1KMT2ATERTSTAT3 | |
| SCHEMBL17483942 | 0.92 | CDC25A (0.36) | KDM4EPPARGPPARACDC25ACDC25B | |
| SCHEMBL17483961 | 0.90 | TERT (0.30) | TERT | |
| SCHEMBL17484032 | 0.90 | PPARG (0.34) | TERTSTAT3HIF1APPARGPPARA | |
| SCHEMBL17483954 | 0.90 | CDC25A (0.36) | KDM4EMEN1KMT2ATERTSTAT3 | |
| SCHEMBL17190554 | 0.90 | PPARG (0.35) | PPARGPPARACDC25ACDC25BCDC25C | |
| SCHEMBL17190553 | 0.90 | PPARG (0.35) | PPARGPPARACDC25ACDC25BCDC25C | |
| SCHEMBL17484030 | 0.90 | TOP1 (0.34) | KDM4EKMT2ATERTPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016498-A1 | METHOD FOR PRODUCING PDI DERIVATIVES | UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE (ES) | 2016-02-04 | — | — | WO | disclosed |