Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.33 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.33 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483872 | 0.97 | TERT (0.34) | TOP1HTR1AAPPBCHEACHE | |
| SCHEMBL17483878 | 0.90 | PPARG (0.35) | TERTMAPTSMPD1 | |
| SCHEMBL17483956 | 0.90 | CDC25A (0.36) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL17483873 | 0.90 | KDM4E (0.32) | TERTTNFSTAT3HIF1AKDM4E | |
| SCHEMBL17483942 | 0.89 | CDC25A (0.36) | KDM4EALDH1A1LMNAMAPTPTPN1 | |
| SCHEMBL17483961 | 0.87 | TERT (0.30) | TERTMAPT | |
| SCHEMBL17483953 | 0.87 | TERT (0.30) | TERTMAPT | |
| SCHEMBL17483952 | 0.87 | TERT (0.34) | TERTTNFSTAT3HIF1AKDM4E | |
| SCHEMBL17483954 | 0.87 | CDC25A (0.36) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL17484032 | 0.87 | PPARG (0.34) | TERTSTAT3HIF1AMAPTSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016498-A1 | METHOD FOR PRODUCING PDI DERIVATIVES | UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE (ES) | 2016-02-04 | — | — | WO | disclosed |