Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484161 | 0.88 | KDR (0.67) | KDRPDGFRB | |
| SCHEMBL17484155 | 0.83 | KDR (0.69) | KDRPDGFRB | |
| SCHEMBL17484159 | 0.83 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17590015 | 0.82 | KDR (0.57) | KDRPDGFRB | |
| SCHEMBL15248099 | 0.75 | KDR (0.58) | KDRPDGFRB | |
| SCHEMBL30109408 | 0.74 | ALDH1A1 (0.54) | KDRPDGFRB | |
| SCHEMBL19846157 | 0.74 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL18886195 | 0.73 | KDR (0.66) | KDRPDGFRB | |
| SCHEMBL1490676 | 0.72 | PLOD2 (0.60) | — | |
| SCHEMBL15238385 | 0.72 | KDR (0.69) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255096-B1 | Substituted 1,2,3,4-tetrahydrobenzo[C][2,7] naphthyridines and derivatives thereof as kinase inhibitors | ALLERGAN, INC. (US) | 2016-02-09 | — | — | US | claimed |
| US-9255096-B1 | Substituted 1,2,3,4-tetrahydrobenzo[C][2,7] naphthyridines and derivatives thereof as kinase inhibitors | ALLERGAN, INC. (US) | 2016-02-09 | — | — | US | disclosed |
| US-9255096-B1 | Substituted 1,2,3,4-tetrahydrobenzo[C][2,7] naphthyridines and derivatives thereof as kinase inhibitors | ALLERGAN, INC. (US) | 2016-02-09 | — | — | US | disclosed |