SCHEMBL17484307

SCHEMBL17484307

C[C@H]1CN(C2CCNCC2)CCN1C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.35
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7469460 1.00 CHRM2 (0.35) CHRM2ALDH1A1
SCHEMBL31209273 0.89 HTR6 (0.39) CHRM2
SCHEMBL31208818 0.89 HTR6 (0.39) CHRM2
SCHEMBL29138764 0.82 ALDH1A1 (0.37) CHRM2ALDH1A1
SCHEMBL29335274 0.82 ALDH1A1 (0.37) CHRM2ALDH1A1
SCHEMBL21120632 0.82 ALDH1A1 (0.37) CHRM2ALDH1A1
SCHEMBL16822468 0.80 HTR2A (0.32)
SCHEMBL10274614 0.80 ALDH1A1 (0.47) ALDH1A1
SCHEMBL16822613 0.80 HTR2A (0.32)
SCHEMBL27811142 0.80 ALDH1A1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016015597-A1 COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2016-02-04 WO disclosed