SCHEMBL17484348

SCHEMBL17484348

C=C(C)C(=O)Oc1ccc(CCc2ccc(-c3ccc(CCCO[Si](C)(C)C(C)(C)C)cc3CC)c(F)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
ELANE P08246 1/20 0.31
RARB P10826 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17484377 0.91 POLB (0.37)
SCHEMBL17477145 0.85 RARB (0.36) THRBELANERARB
SCHEMBL17484376 0.85 ESR1 (0.34) RARB
SCHEMBL17477149 0.84 S1PR1 (0.38) RARB
SCHEMBL17484350 0.83 PTGS2 (0.37) THRBELANERARB
SCHEMBL17484412 0.79 RARB (0.35) THRBELANERARB
SCHEMBL20412535 0.79 ELANE (0.33) THRBELANERARB
SCHEMBL17484442 0.78 TDP1 (0.36)
SCHEMBL28457603 0.78 TBXAS1 (0.36)
SCHEMBL17484454 0.77 RARB (0.36) THRBRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294426-B2 Liquid crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2019-05-21 US disclosed
US-10294426-B2 Liquid crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2019-05-21 US disclosed
US-20180208848-A1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-07-26 US disclosed
US-20180208848-A1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-07-26 US disclosed
US-20180208848-A1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-07-26 US disclosed
WO-2016015803-A1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2016-02-04 WO disclosed