Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484351 | 0.89 | ELANE (0.41) | PTGS2ELANETHRBKMT2AATM | |
| SCHEMBL17791331 | 0.87 | ELANE (0.44) | ELANETHRBKMT2AATMAKT1 | |
| SCHEMBL22083049 | 0.84 | FFAR4 (0.32) | KMT2AFFAR4 | |
| SCHEMBL17484350 | 0.83 | PTGS2 (0.37) | PTGS2ELANETHRBKMT2AATM | |
| SCHEMBL17484196 | 0.81 | ELANE (0.36) | PTGS2ELANEKMT2AATMFFAR1 | |
| SCHEMBL18258061 | 0.81 | ELANE (0.46) | ELANEKMT2AATMPPARASRD5A2 | |
| SCHEMBL14329748 | 0.80 | THRB (0.56) | ELANETHRBKMT2AATMAKT1 | |
| SCHEMBL17547350 | 0.79 | ELANE (0.47) | ELANEKMT2AATMPPARASRD5A2 | |
| SCHEMBL17484464 | 0.79 | ELANE (0.49) | PTGS2ELANETHRBKMT2AATM | |
| SCHEMBL17484463 | 0.78 | ELANE (0.35) | PTGS2ELANEKMT2AATMFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |