Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20412536 | 0.91 | POLB (0.40) | MAOBALDH1A1LMNAMEN1USP2 | |
| SCHEMBL17477156 | 0.85 | POLB (0.41) | MAOBALDH1A1LMNAMEN1USP2 | |
| SCHEMBL17484445 | 0.83 | RARB (0.42) | MAOBALDH1A1LMNAMEN1USP2 | |
| SCHEMBL17484350 | 0.82 | PTGS2 (0.37) | MAOBKMT2AMAOAVDRFFAR1 | |
| SCHEMBL17484390 | 0.81 | POLB (0.37) | MAOBALDH1A1LMNAMAOAS1PR1 | |
| SCHEMBL17484405 | 0.80 | RARB (0.36) | — | |
| SCHEMBL21507757 | 0.80 | FFAR4 (0.32) | MAOBMAOAS1PR1S1PR3VDR | |
| SCHEMBL17484391 | 0.80 | POLB (0.38) | MAOBALDH1A1LMNAMEN1USP2 | |
| SCHEMBL17484380 | 0.80 | S1PR1 (0.39) | MAOBALDH1A1MAOAS1PR1S1PR3 | |
| SCHEMBL21507772 | 0.79 | POLB (0.39) | MAOBALDH1A1LMNAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |