Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748190 | 0.89 | HTR6 (0.56) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL1752646 | 0.88 | HTR6 (0.55) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL475545 | 0.82 | HTR6 (0.57) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL1748343 | 0.81 | HTR6 (0.59) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| Tert-Butyl Formate SCHEMBL28805288 | 0.80 | HTR6 (0.47) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL14941307 | 0.77 | LMNA (0.75) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL1748558 | 0.76 | SMN1; SMN2 (0.52) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL27933545 | 0.75 | SMN1; SMN2 (0.51) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5276988 | 0.73 | SERPINE1 (0.47) | HTR6MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5273517 | 0.73 | HTR6 (0.79) | HTR6MAPTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968538-B2 | Substituted arylamine compounds and methods of treatment | GALENEA CORP. (US) | 2011-06-28 | — | — | US | claimed |