Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903097 | 1.00 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| SCHEMBL209471 | 1.00 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| Piperazine SCHEMBL28106509 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL27587923 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL1899181 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| SCHEMBL3432550 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| SCHEMBL3387061 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL30163937 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| SCHEMBL3383287 | 0.98 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL29250334 | 0.97 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1ALOX15TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177598-B1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INST NAT SANTE RECH MED (FR) | 2019-08-28 | — | — | EP | disclosed |
| US-10351539-B2 | Macrocyclic complexes, their process of preparation and use as PET imaging agents | INSERM (Institut National de la Santé et de le Recherche Médicale) (FR) | 2019-07-16 | — | — | US | disclosed |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| WO-2016016272-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-02-04 | — | — | WO | disclosed |
| US-9023656-B2 | Reactive mass labels | ELECTROPHORETICS LIMITED (GB) | 2015-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351539-B2 | Macrocyclic complexes, their process of preparation and use as PET imaging agents | MPI, PAICS, TFEB | ALDH1A1 1961/4885L3MBTL1 4844/4885ALOX15 3374/4885 |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | MPI, PAICS, TFEB | ALDH1A1 1961/4885L3MBTL1 4844/4885ALOX15 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.