Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877103 | 1.00 | KDM4E (0.46) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL29937687 | 1.00 | KDM4E (0.46) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL30198446 | 0.75 | CYP1A2 (0.60) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL1672650 | 0.75 | CYP1A2 (0.60) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL30527184 | 0.75 | CYP1A2 (0.60) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL11389060 | 0.74 | KDM4E (0.41) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL27836789 | 0.73 | MAPT (0.45) | KDM4EMAPTCYP1A2NPC1BACE1 | |
| SCHEMBL30070996 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL31029246 | 0.73 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTACHECYP1A2 | |
| SCHEMBL7900625 | 0.71 | KDM4E (0.52) | KDM4EGPR3EGFRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117320551-A | Seed treatment composition | 先正达农作物保护股份公司 | 2023-12-29 | — | — | CN | claimed |
| CN-112843069-A | Application of azelnylquinazoline derivative in preparation of drugs for treating lung cancer | 浙江工业大学 | 2021-05-28 | — | — | CN | claimed |
| CN-109251196-B | Aminobenzo [ d ] aza-quinazoline compound and preparation method and application thereof | 浙江工业大学 | 2020-11-13 | — | — | CN | claimed |
| CN-108014112-B | Application of o-toluidine amino acetamido benzo [ d ] aza-based quinazoline compound in preparation of drugs for treating lung cancer | 浙江工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108129460-B | Methoxyphenylbenzo [ d ] aza-quinazoline compound and preparation and application thereof | 浙江工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108329300-B | Nitrobenzo [ d ] aza-quinazoline compound and preparation method and application thereof | 浙江工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108324718-B | Application of cyclohexyl methoxy formyl amino chloro benzo aza group quinazoline compound in leukemia treatment drug | 浙江工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108014115-B | Application of pivaloylaminomethoxyphenyl benzo [ d ] aza-quinazoline compound in preparation of lung cancer treatment drug | 浙江工业大学 | 2020-10-02 | — | — | CN | claimed |
| CN-108125962-B | Application of benzo [ d ] aza-quinazoline compound in preparation of drugs for treating lung cancer | 浙江工业大学 | 2020-08-21 | — | — | CN | claimed |
| CN-108143736-B | Application of butyrylaminobenzo [ d ] aza-based quinazoline in preparation of drugs for treating lung cancer | 浙江工业大学 | 2020-08-21 | — | — | CN | claimed |
| CN-108117542-B | Propionyl amino methoxyphenyl benzo [ d ] nitrogen hetero-pinyl quinazoline compound, preparation and application | 浙江工业大学 | 2019-12-24 | — | — | CN | claimed |
| CN-104230826-B | 2 fluoro quinazoline cyclics and preparation method thereof and pharmaceutical usage | 复旦大学 | 2017-03-29 | — | — | CN | claimed |
| CN-103200936-B | Novel N-hydroxybenzamide compounds for the treatment of cancer | HOFFMANN LA ROCHE | 2015-03-11 | — | — | CN | claimed |
| CN-103068821-B | 4 - aminoquinazolin- 2 - yl - 1 - pyrrazole - 4 - carboxylic acid compounds as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-02-25 | — | — | CN | claimed |
| CN-104230826-A | 2-fluoroquinazoline cyclic compounds, and preparation method and medicinal application thereof | UNIV FUDAN | 2014-12-24 | — | — | CN | claimed |
| CN-101891709-B | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2012-11-21 | — | — | CN | claimed |
| CN-102573479-A | 3-[1-(3-haloalkyl)-triazolyl]-phenyl-sulfide derivatives for use as acaricides and insecticides | BAYER CROPSCIENCE AG | 2012-07-11 | — | — | CN | claimed |
| CN-102471291-A | 3-triazolylphenyl-substituted sulfide derivatives for use as acaricides and insecticides | BAYER CROPSCIENCE AG | 2012-05-23 | — | — | CN | claimed |
| CN-102417505-A | Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof | UNIV NANKAI | 2012-04-18 | — | — | CN | claimed |
| CN-102382108-A | Tetrazole compounds containing 1,2,3-bismuththiol methylene, preparation methods for same and application thereof | UNIV NANKAI | 2012-03-21 | — | — | CN | claimed |