Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486221 | 0.86 | ALDH1A1 (0.37) | ALOX5APFEN1PGR | |
| SCHEMBL17486108 | 0.79 | FEN1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL17486161 | 0.78 | FEN1 (0.34) | ALOX5APFEN1RPS6KA3 | |
| SCHEMBL24602339 | 0.73 | RPS6KA3 (0.45) | ALOX5APFEN1PTGS2RPS6KA3DHODH | |
| SCHEMBL20687810 | 0.70 | ALOX5AP (0.41) | ALOX5APFEN1PTGS2RPS6KA3DHODH | |
| SCHEMBL22765221 | 0.70 | FEN1 (0.42) | ALOX5APFEN1PDK2DHODHCNR2 | |
| SCHEMBL24767202 | 0.68 | WNT3A (0.46) | — | |
| SCHEMBL24701899 | 0.67 | TDP1 (0.39) | PDK2CNR2 | |
| SCHEMBL17486216 | 0.67 | MAPK1 (0.37) | PTGS2PGR | |
| SCHEMBL17486219 | 0.67 | ALDH1A1 (0.35) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |