Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
| ▸ | RARA | P10276 | 6/20 | 0.34 |
| ▸ | RARB | P10826 | 6/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 6/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485957 | 0.86 | RARB (0.36) | RARARARBRXRARARGPGR | |
| SCHEMBL17486024 | 0.85 | BACE1 (0.35) | BACE1RARARARBRXRARARG | |
| SCHEMBL20805582 | 0.84 | BACE1 (0.39) | BACE1RARARARBALOX5APFEN1 | |
| SCHEMBL17486004 | 0.79 | RARA (0.34) | RARARARBRXRARARGPGR | |
| SCHEMBL19295091 | 0.78 | LPL (0.35) | BACE1RARARARBRXRARARG | |
| SCHEMBL16998454 | 0.77 | RARB (0.45) | RARARARBRXRARARG | |
| SCHEMBL16998885 | 0.77 | RARB (0.45) | RARARARBRXRARARG | |
| SCHEMBL19794375 | 0.74 | RARG (0.40) | RARARARBRXRARARGALOX5AP | |
| SCHEMBL24523706 | 0.74 | CYP11B1 (0.43) | KMOALOX5APFEN1NPC1RAB9A | |
| SCHEMBL16998584 | 0.73 | RARB (0.48) | RARARARBRXRARARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |