Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | MC5R | P33032 | 2/20 | 0.35 |
| ▸ | MC3R | P41968 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MC1R | Q01726 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486587 | 0.92 | IGF1R (0.36) | IGF1RMC4RMC5RMC3RKMT2A | |
| SCHEMBL17354506 | 0.91 | IGF1R (0.38) | IGF1RMC4RMC5RMC3RKMT2A | |
| SCHEMBL13774 | 0.90 | IDH2 (0.36) | IGF1RMC4RMC5RMC3R | |
| SCHEMBL17354368 | 0.87 | MC4R (0.37) | MC4RMC5RMC3RKMT2AMEN1 | |
| SCHEMBL17354473 | 0.87 | IGF1R (0.37) | IGF1RCHEK1 | |
| SCHEMBL17486571 | 0.86 | IGF1R (0.38) | IGF1RKMT2AMEN1MAPT | |
| SCHEMBL13700 | 0.85 | MC4R (0.35) | IGF1RMC4RMC5RMC3RMC1R | |
| SCHEMBL17354480 | 0.85 | IGF1R (0.36) | IGF1RKMT2AMEN1CHEK1LMNA | |
| SCHEMBL14850261 | 0.85 | IGF1R (0.39) | IGF1RMC4RMC5RMC3RKMT2A | |
| SCHEMBL17486539 | 0.85 | KMT2A (0.37) | IGF1RKMT2AMEN1GAACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | IGF1R 4795/4885MC4R 2989/4885MC5R 3036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.