Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923023 | 0.95 | TSHR (0.40) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL642391 | 0.86 | TSHR (0.53) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL16923019 | 0.85 | TSHR (0.35) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL16923025 | 0.84 | TSHR (0.35) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14826035 | 0.77 | TSHR (0.34) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL16661604 | 0.75 | TSHR (0.61) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL2066081 | 0.75 | TSHR (0.61) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL18371651 | 0.75 | TSHR (0.61) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL2006386 | 0.75 | TSHR (0.61) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL18472006 | 0.74 | EPHX2 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036490-A1 | GASKET | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20170037212-A1 | METHOD FOR MODIFYING SURFACE AND SURFACE MODIFIED ELASTIC BODY | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-02-09 | — | — | US | disclosed |
| US-20160033042-A1 | GASKET | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-02-04 | — | — | US | disclosed |