SCHEMBL642391

SCHEMBL642391

C[Si]1(CCCOCC2CO2)CCCCO1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
MAPK1 P28482 1/20 0.38
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17486715 0.86 TSHR (0.44) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL16923023 0.82 TSHR (0.40) TSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL10014097 0.80
SCHEMBL17133617 0.80 TSHR (0.50) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL8002486 0.77 TSHR (0.46) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL1414615 0.76 TSHR (0.45) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL9714964 0.73
SCHEMBL12377658 0.73 TSHR (0.45) TSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL17549553 0.73 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL17549551 0.73 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9012725-A None JP disclosed
WO-2023195840-A1 AN APPARATUS FOR SURFACE AND AIR DISINFECTION GERMICIDAL TECHNOLOGY SDN BHD (MY) 2023-10-12 WO disclosed
US-10065882-B2 Composition for forming solar cell electrode and electrode fabricated using the same SAMSUNG SDI CO., LTD. (KR) 2018-09-04 US disclosed
US-20170327410-A1 COMPOSITION FOR FORMING SOLAR CELL ELECTRODE AND ELECTRODE FABRICATED USING THE SAME CHANGZHOU FUSION NEW MATERIAL CO. LTD (CN) 2017-11-16 US disclosed
US-8119744-B2 Curable silicone composition DOW CORNING TORAY CO., LTD. (JP) 2012-02-21 US disclosed
US-7994246-B2 Curable silicone composition and electronic component DOW CORNING TORAY COMPANY, LTD. (JP) 2011-08-09 US disclosed
EP-2201068-B1 CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF DOW CORNING TORAY CO LTD (JP) 2011-06-29 EP disclosed
US-20100140537-A1 Curable Silicone Composition DOW CORNING TORAY CO., LTD. (JP) 2010-06-10 US disclosed
EP-1776420-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION DOW CORNING TORAY CO LTD (JP) 2010-02-24 EP disclosed
US-20080262157-A1 Curable Organopolysiloxane Composition DOW CORNING TORAY COMPANY, LTD. (JP) 2008-10-23 US disclosed
EP-1776420-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2007-04-25 EP disclosed
WO-2005123839-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2005-12-29 WO disclosed
US-5837792-A MODIFIED POLYSILOXANES WITH HYDROXYPHENYLDIARYL-S-TRIAZINE GROUPS FOR LIGHT, HEAT AND OXYGEN STABILIZATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US disclosed
JP-H0912725-A POLYSILOXANE PHOTO STABILIZER CIBA GEIGY AG 1997-01-14 JP disclosed
US-5372854-A Maintaining uniform moisture content in cotton bales by spraying before compression with a dimethylsiloxane homo- or copolymer TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1994-12-13 US disclosed
EP-0468626-B1 Cotton bales and method of producing same TAKEMOTO OIL & FAT CO LTD (JP) 1994-06-01 EP disclosed
US-5188224-A Water insoluble, protective coating of polysiloxane adhesive coating attached to lint cotton TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1993-02-23 US disclosed
EP-0202594-B1 HYDROPHILIC SILICONE RUBBER MOULDINGS AND PROCESS FOR PREPARING THESE CIBA-GEIGY AG (CH) 1992-08-05 EP disclosed
EP-0202594-A2 Hydrophilic silicone rubber mouldings and process for preparing these CIBA-GEIGY AG (CH) 1986-11-26 EP disclosed