Sugi Predict

Sugi Predict / Compounds / SCHEMBL1748728

SCHEMBL1748728

SCHEMBL1748728

Cc1ccc(S(=O)(=O)n2ccc3c(Cl)c(F)cnc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ BRD4 O60885 3/20 0.44
▸ PKM P14618 2/20 0.40
▸ POLB P06746 1/20 0.39
▸ ALDH3A1 P30838 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ NOD1 Q9Y239 1/20 0.39
▸ RAPGEF4 Q8WZA2 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ PDE4A P27815 1/20 0.36
▸ PDE4B Q07343 1/20 0.36
▸ PDE4C Q08493 1/20 0.36
▸ PDE4D Q08499 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HTR6 P50406 2/20 0.36
▸ MAPT P10636 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28335381 0.87 L3MBTL1 (0.51) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL30509477 0.87 L3MBTL1 (0.51) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL16041786 0.87 CYP2C19 (0.48) L3MBTL1PKMHTTMEN1KMT2A
SCHEMBL29605637 0.87 L3MBTL1 (0.51) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL16052697 0.87 L3MBTL1 (0.51) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL1356064 0.87 L3MBTL1 (0.51) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL10008513 0.86 L3MBTL1 (0.50) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL1356125 0.85 L3MBTL1 (0.49) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL20535940 0.85 L3MBTL1 (0.49) L3MBTL1BRD4PKMPOLBALDH3A1
SCHEMBL1933799 0.82 L3MBTL1 (0.47) L3MBTL1BRD4PKMPOLBALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087613-A1 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS, PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2026-04-30 — — WO disclosed
US-20260028346-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 — — US disclosed
US-20260028345-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 — — US disclosed
EP-1799691-B1 NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS AVENTIS PHARMA SA (FR) 2011-12-21 — — EP disclosed
US-7968566-B2 Pyrrolo(2,3-b) pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2011-06-28 — — US disclosed
US-20100256141-A1 NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS AVENTIS PHARMA S.A. (FR) 2010-10-07 — — US disclosed
US-7786114-B2 Bis-azaindole derivatives, preparation and pharmaceutical use thereof as kinase inhibitors AVENTIS PHARMA S.A. (FR) 2010-08-31 — — US disclosed
US-20090233956-A1 NOVEL PYRROLO(2,3-b) PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS AVENTIS PHARMA S.A. (FR) 2009-09-17 — — US disclosed
US-7528147-B2 Pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2009-05-05 — — US disclosed
US-20080045561-A1 Novel Bis-Azaindole Derivatives, Preparation And Pharmaceutical Use Thereof As Kinase Inhibitors AVENTIS PHARMA S.A. (FR) 2008-02-21 — — US disclosed
EP-1799691-A1 NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS Aventis Pharma S.A. (FR) 2007-06-27 — — EP disclosed
US-20070093480-A1 Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2007-04-26 — — US disclosed
CN-1950083-A Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA SA (FR) 2007-04-18 — — CN disclosed
WO-2006037875-A1 NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS AVENTIS PHARMA S.A. (FR) 2006-04-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028345-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, TEC L3MBTL1 2434/4885BRD4 486/4885PKM 1379/4885
US-20080045561-A1 Novel Bis-Azaindole Derivatives, Preparation And Pharmaceutical Use Thereof As Kinase Inhibitors BRSK2, KSR2, CDK2 L3MBTL1 4205/4885BRD4 454/4885PKM 618/4885
US-20090233956-A1 NOVEL PYRROLO(2,3-b) PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS MAP3K19, MAP4K2, MAP3K1 L3MBTL1 4601/4885BRD4 630/4885PKM 282/4885
US-20100256141-A1 NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS BRSK2, KSR2, CDK2 L3MBTL1 4205/4885BRD4 454/4885PKM 618/4885
US-20260028346-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, LYN L3MBTL1 2869/4885BRD4 627/4885PKM 1551/4885
US-20070093480-A1 Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors MAP3K19, MAP4K2, MAP3K1 L3MBTL1 4601/4885BRD4 630/4885PKM 282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.