Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 11/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17487550 | 0.85 | HDAC6 (0.54) | HDAC1HDAC6KMT2APOLBRAB9A | |
| SCHEMBL17488137 | 0.82 | F10 (0.45) | HDAC1F10HDAC6KMT2APOLB | |
| SCHEMBL18960435 | 0.81 | F10 (0.52) | F10KMT2ARAB9ANPC1KLKB1 | |
| SCHEMBL17488141 | 0.78 | RAB9A (0.43) | HDAC1HDAC6KMT2ARAB9ANPC1 | |
| SCHEMBL17487452 | 0.77 | RAB9A (0.47) | HDAC6KMT2APOLBRAB9ANPC1 | |
| SCHEMBL17487684 | 0.77 | RAB9A (0.53) | HDAC6KMT2ARAB9ANPC1TP53 | |
| SCHEMBL17488015 | 0.77 | RAB9A (0.42) | HDAC6KMT2APOLBRAB9ANPC1 | |
| SCHEMBL17487379 | 0.77 | RAB9A (0.48) | KMT2APOLBRAB9ANPC1CYP2C8 | |
| SCHEMBL17488218 | 0.76 | RAB9A (0.46) | HDAC6KMT2APOLBRAB9ANPC1 | |
| SCHEMBL17487313 | 0.76 | HDAC6 (0.64) | HDAC1HDAC6KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |