Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488012 | 0.82 | HDAC1 (0.52) | F10KLKB1HDAC6DGAT1CYP2C8 | |
| SCHEMBL18965854 | 0.82 | F10 (0.46) | F10KLKB1KMT2ANPC1RAB9A | |
| SCHEMBL17488138 | 0.81 | RAB9A (0.37) | HDAC6DGAT1KCNH2KMT2ANPC1 | |
| SCHEMBL17488105 | 0.80 | RAB9A (0.41) | DGAT1KCNH2RAB9ASMN1; SMN2 | |
| SCHEMBL17487996 | 0.80 | RAB9A (0.45) | HDAC6KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17488011 | 0.80 | RIPK1 (0.37) | HDAC6DGAT1KCNH2KMT2APOLB | |
| SCHEMBL17488237 | 0.80 | RAB9A (0.40) | HDAC6KMT2APOLBNPC1RAB9A | |
| SCHEMBL17488096 | 0.78 | RAB9A (0.42) | HDAC6KMT2APOLBNPC1RAB9A | |
| SCHEMBL17487716 | 0.77 | SMN1; SMN2 (0.43) | HDAC6KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17488013 | 0.77 | RAB9A (0.39) | DGAT1KCNH2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |