Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488087 | 0.94 | P2RX3 (0.40) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL17487750 | 0.93 | P2RX3 (0.44) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL17487718 | 0.88 | RAB9A (0.43) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL17488195 | 0.85 | TP53 (0.41) | TP53RAB9ASMN1; SMN2RAF1KDR | |
| SCHEMBL17487483 | 0.84 | P2RX3 (0.38) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL18965864 | 0.83 | CYP3A4 (0.51) | RAB9ASMN1; SMN2P2RX3CYP3A4 | |
| SCHEMBL17488014 | 0.83 | POLB (0.50) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL17487452 | 0.81 | RAB9A (0.47) | TP53RAB9ASMN1; SMN2CYP3A4DGAT1 | |
| SCHEMBL17488151 | 0.80 | RAB9A (0.42) | TP53RAB9ASMN1; SMN2P2RX3RAF1 | |
| SCHEMBL17487320 | 0.78 | RAB9A (0.48) | TP53RAB9ASMN1; SMN2KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |