Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488322 | 0.92 | P2RX3 (0.39) | LMNATP53P2RX3NPC1RAB9A | |
| SCHEMBL18965985 | 0.91 | CYP3A4 (0.40) | LMNATP53P2RX3 | |
| SCHEMBL18965884 | 0.88 | LMNA (0.39) | LMNATP53P2RX3NPC1RAB9A | |
| SCHEMBL17488319 | 0.86 | TP53 (0.39) | LMNATP53P2RX3NPC1RAB9A | |
| SCHEMBL17488247 | 0.84 | LMNA (0.38) | LMNATP53P2RX3NPC1RAB9A | |
| SCHEMBL18965822 | 0.84 | CYP3A4 (0.45) | P2RX3NPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL18965888 | 0.82 | P2RX3 (0.39) | LMNATP53P2RX3THRBSMN1; SMN2 | |
| SCHEMBL17488317 | 0.82 | MCHR1 (0.37) | P2RX3SMN1; SMN2KDR | |
| SCHEMBL17488024 | 0.81 | NPC1 (0.39) | TP53NPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL17488049 | 0.79 | MAPT (0.34) | LMNATP53P2RX3SMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |