Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | BCR | P11274 | 4/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488072 | 0.94 | CXCL8 (0.43) | CXCL8NOD1KMT2ADHFRNTRK1 | |
| SCHEMBL17488202 | 0.82 | NOD1 (0.46) | CXCL8NOD1KMT2ADHFRNTRK1 | |
| SCHEMBL17488070 | 0.80 | NOD1 (0.52) | CXCL8NOD1KMT2ANTRK1SCN5A | |
| SCHEMBL17488080 | 0.78 | IDH1 (0.40) | NTRK1MCHR1MCHR2IDH1 | |
| SCHEMBL17488185 | 0.76 | IDH1 (0.41) | NTRK1SCN9AMCHR1MCHR2IDH1 | |
| SCHEMBL17488184 | 0.75 | IDH1 (0.42) | MCHR1MCHR2IDH1 | |
| SCHEMBL17488075 | 0.73 | KMT2A (0.52) | CXCL8NOD1KMT2ANTRK1IDH1 | |
| SCHEMBL17488177 | 0.72 | ALOX5AP (0.38) | NTRK1SCN9AMCHR1ABL1BCR | |
| SCHEMBL17488288 | 0.68 | NTRK1 (0.41) | CXCL8NOD1KMT2ANTRK1IDH1 | |
| SCHEMBL17488178 | 0.68 | NTRK1 (0.42) | CXCL8NOD1KMT2ADHFRNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |