Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488043 | 0.92 | RAB9A (0.39) | RAB9ASMN1; SMN2TP53ROCK2LMNA | |
| SCHEMBL17487996 | 0.88 | RAB9A (0.45) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487495 | 0.85 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488236 | 0.84 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488124 | 0.84 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488103 | 0.84 | SCN9A (0.47) | RAB9ASMN1; SMN2TP53KDRTEK | |
| SCHEMBL17487488 | 0.84 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487326 | 0.83 | RAB9A (0.46) | RAB9ASMN1; SMN2TP53ROCK2LMNA | |
| SCHEMBL17488033 | 0.83 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488041 | 0.83 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |