Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488159 | 0.89 | RAB9A (0.41) | SCN9AKDRTEKTP53RAB9A | |
| SCHEMBL17488240 | 0.88 | RAB9A (0.41) | SCN9AKDRTEKTP53RAB9A | |
| SCHEMBL17488105 | 0.88 | RAB9A (0.41) | KCNH2TP53RAB9ASMN1; SMN2 | |
| SCHEMBL17488336 | 0.87 | SCN9A (0.42) | SCN9AKCNH2SCN7ASCN5AKDR | |
| SCHEMBL17488013 | 0.86 | RAB9A (0.39) | KCNH2KDRTP53RAB9ASMN1; SMN2 | |
| SCHEMBL17488108 | 0.84 | RAB9A (0.43) | KDRTEKTP53RAB9ASMN1; SMN2 | |
| SCHEMBL17488338 | 0.84 | SCN9A (0.44) | SCN9AKCNH2SCN7ASCN5AKDR | |
| SCHEMBL17487504 | 0.83 | RAB9A (0.41) | KDRTP53RAB9ASMN1; SMN2 | |
| SCHEMBL17488043 | 0.83 | RAB9A (0.39) | TEKMCHR1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL17488236 | 0.82 | RAB9A (0.42) | KDRTEKMCHR1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |