Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.38 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.38 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454201 | 0.78 | ALDH1A1 (0.70) | KDM4EHSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL17488283 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL17488268 | 0.73 | CYP3A4 (0.45) | ALDH1A1SMN1; SMN2HTTCYP3A4NPC1 | |
| SCHEMBL18965901 | 0.72 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL17487355 | 0.72 | SMN1; SMN2 (0.44) | KDM4EHSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL521102 | 0.71 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3877108 | 0.71 | ATM (0.39) | KDM4EHSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11435533 | 0.70 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6592993 | 0.70 | MCHR1 (0.39) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18960407 | 0.70 | NPC1 (0.59) | ALDH1A1SMN1; SMN2HTTCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |