Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458651 | 0.90 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL5114079 | 0.85 | RAB9A (0.64) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL6204453 | 0.83 | RAB9A (0.62) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9698171 | 0.83 | RAB9A (0.62) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL12136194 | 0.81 | RAB9A (0.68) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9696974 | 0.80 | RAB9A (0.55) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL17488258 | 0.78 | KDM4E (0.58) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL5811766 | 0.77 | RAB9A (0.62) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9568272 | 0.75 | SMN1; SMN2 (0.68) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL20715326 | 0.75 | KDM4E (0.65) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |
| US-8969577-B2 | Curable composition comprising a thermolatent base | BASF SE (DE) | 2015-03-03 | — | — | US | disclosed |
| US-8969577-B2 | Curable composition comprising a thermolatent base | BASF SE (DE) | 2015-03-03 | — | — | US | disclosed |
| EP-2367794-B1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| US-20110245375-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | BASF SE (DE) | 2011-10-06 | — | — | US | disclosed |
| US-20110245375-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | BASF SE (DE) | 2011-10-06 | — | — | US | disclosed |
| WO-2010057922-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | BASF SE (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245375-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | COIL, MAPT, ASH2L | ALDH1A1 2185/4885KDM4E 1082/4885TSHR 4677/4885 |
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | ALDH1A1 39/4885KDM4E 2704/4885TSHR 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.