Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960400 | 0.86 | HPGD (0.46) | HPGDKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL18960401 | 0.79 | IDH1 (0.47) | HPGDKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL17488070 | 0.76 | NOD1 (0.52) | KMT2AGAAMAPK1NTRK1HTT | |
| SCHEMBL17487443 | 0.75 | TYMS (0.47) | KMT2AALDH1A1POLBNTRK1NTRK2 | |
| SCHEMBL2610178 | 0.73 | KDM4E (0.55) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL15225116 | 0.71 | MAPT (0.77) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL2607600 | 0.70 | CTSD (0.56) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1514818 | 0.70 | KDM4E (0.75) | HPGDKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL13182089 | 0.69 | MEN1 (0.75) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL17488202 | 0.68 | NOD1 (0.46) | KMT2AMCHR1MCHR2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |