Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488100 | 0.89 | RAB9A (0.41) | GRM4RAB9ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17488015 | 0.88 | RAB9A (0.42) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17487452 | 0.86 | RAB9A (0.47) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17488141 | 0.83 | RAB9A (0.43) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17488308 | 0.83 | GRM4 (0.40) | GRM4RAB9ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17488113 | 0.82 | RAB9A (0.44) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18960417 | 0.81 | SMN1; SMN2 (0.43) | GRM4RAB9ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17488152 | 0.79 | RAB9A (0.39) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17487732 | 0.79 | RAB9A (0.45) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17487957 | 0.78 | CYP3A4 (0.41) | RAB9ASMN1; SMN2TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |