Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488102 | 0.91 | RAB9A (0.36) | GRM4RIPK1P2RX3RAB9ALMNA | |
| SCHEMBL17488011 | 0.89 | RIPK1 (0.37) | RIPK1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL17488105 | 0.88 | RAB9A (0.41) | RIPK1P2RX3RAB9ALMNACYP1A2 | |
| SCHEMBL17488138 | 0.85 | RAB9A (0.37) | RIPK1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL17488013 | 0.85 | RAB9A (0.39) | RIPK1P2RX3RAB9ALMNACYP1A2 | |
| SCHEMBL17488304 | 0.83 | GRM4 (0.43) | GRM4PIM1P2RX3RAB9ALMNA | |
| SCHEMBL18965841 | 0.82 | CYP3A4 (0.38) | GRM4P2RX3RAB9ALMNAKMT2A | |
| SCHEMBL17488158 | 0.82 | RIPK1 (0.35) | RIPK1RAB9ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17487717 | 0.82 | RAB9A (0.39) | RIPK1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL17487676 | 0.81 | CYP3A4 (0.36) | P2RX3RAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |