Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18611912 | 1.00 | KDM4E (0.37) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL20466161 | 1.00 | KDM4E (0.37) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL17488442 | 0.98 | KDM4E (0.36) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL23945337 | 0.86 | KDM4E (0.35) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL25725620 | 0.85 | HRH3 (0.36) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL18908660 | 0.84 | KDM4E (0.44) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL22837632 | 0.84 | KDM4E (0.44) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL22930120 | 0.84 | KDM4E (0.44) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL18908756 | 0.84 | KDM4E (0.44) | KDM4EPOLBTDP1CYP1A2CYP2D6 | |
| SCHEMBL10914222 | 0.84 | KDM4E (0.44) | KDM4EPOLBTDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024442-A1 | BIFUNCTIONAL COMPOUNDS FOR GRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20160030592-A1 | Polyoxazoline Antibody Drug Conjugates | SERINA THERAPEUTICS (AL), INC. | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160030592-A1 | Polyoxazoline Antibody Drug Conjugates | FCGR2A, FCGR3B, FCGR1A | KDM4E 2768/4885POLB 2337/4885TDP1 880/4885 |
| US-20230024442-A1 | BIFUNCTIONAL COMPOUNDS FOR GRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | BTK, XIAP, CBL | KDM4E 1641/4885POLB 1652/4885TDP1 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.