Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 1.00 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475397 | 1.00 | HTR6 (1.00) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| SCHEMBL1748316 | 1.00 | HTR6 (1.00) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| Hydrochloric Acid SCHEMBL475692 | 0.99 | HTR6 (0.98) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| Hydrochloric Acid SCHEMBL1748258 | 0.99 | HTR6 (0.98) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| Hydrochloric Acid SCHEMBL1748380 | 0.99 | HTR6 (0.98) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| Hydrochloric Acid SCHEMBL29391202 | 0.99 | HTR6 (0.98) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| SCHEMBL5958552 | 0.95 | HTR6 (0.90) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| SCHEMBL1748393 | 0.90 | HTR6 (0.82) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| SCHEMBL10077171 | 0.90 | HTR6 (0.82) | HTR6ALKTGFBR1ACVR1BACVR1 | |
| Hydrochloric Acid SCHEMBL1748224 | 0.89 | HTR6 (0.80) | HTR6ALKTGFBR1ACVR1BACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968538-B2 | Substituted arylamine compounds and methods of treatment | GALENEA CORP. (US) | 2011-06-28 | — | — | US | claimed |