SCHEMBL17490443

SCHEMBL17490443

CC1CCC(C2CCC(c3ccc(CCc4ccc(-c5ccc(F)c(F)c5)c(F)c4)c(F)c3F)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
HTR6 P50406 1/20 0.31
MAOB P27338 1/20 0.31
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17490440 0.91 FFAR4 (0.34) FFAR4
SCHEMBL17487973 0.86 RARB (0.32) FFAR4
SCHEMBL12717024 0.84 FFAR4 (0.34) FFAR4
SCHEMBL17490413 0.82 FFAR4 (0.34) FFAR4
SCHEMBL12735518 0.80 FFAR4 (0.35) FFAR4ALOX5APFEN1HTR6
SCHEMBL17490377 0.80 HTR2A (0.33) FFAR4
SCHEMBL17487707 0.80 FFAR4 (0.38) FFAR4
SCHEMBL17487760 0.79 OPRL1 (0.33) ALOX5APFEN1HTR6MAOB
SCHEMBL17490454 0.78 CTSK (0.39) FFAR4ALOX5APFEN1
SCHEMBL12735479 0.78 FFAR4 (0.39) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9441161-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-09-13 US disclosed
US-20160032187-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2016-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160032187-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE OCIAD1, OCIAD2, PIEZO1 FFAR4 1903/4885ALOX5AP 2022/4885FEN1 1850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.